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Objectives: To examine the temporal stability of conditioned pain modulation CPMformerly termed diffuse noxious inhibitory controls, among a sample of patients with chronic pain. The study also examined the factors that might be responsible for the stability of CPM.

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Distinct pain experiences are shaped both by personal attributes and characteristics of sex cpm stimuli. An Individual's capacity for endogenous pain inhibition reflected by conditioned pain modulation [CPM]their resilience, and the pain unpleasantness and salience of painful stimuli can impact their pain perception. Here, we aimed to determine how individual variability in CPM relates to sex and resilience as personal attributes, and pain unpleasantness and salience of the CPM conditioning stimulus CS. We evaluated CPM in healthy participants 51 female and 55 male based on the change in test stimulus pain applied concurrently with a painful CS, both delivered by painful heat. The CS reduced test stimulus pain in only half of the participants CPM subgroupbut did not do so for the other half no-CPM subgroupmany who exhibited pain facilitation.

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Learn more. If you have ly obtained access with your personalplease log in. To examine the temporal stability of conditioned pain modulation CPMformerly termed diffuse noxious inhibitory controls, among a sample of patients with chronic pain. The study also examined the factors that might be responsible for the stability of CPM. In this test-retest study, patients underwent a series of standardized psychophysical pain-testing procedures deed to assess CPM on two separate occasions i.

Overall, provided evidence for the stability of CPM among patients with chronic pain.however, revealed considerable sex differences in the stability of CPM. For women, revealed a ificant test-retest correlation between baseline and follow-up CPM scores.

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For men, however, the test-retest correlation between baseline and follow-up CPM scores was not ificant. of a Fisher's Z-test revealed that the stability of CPM was ificantly greater for women than for men. Follow-up analyses revealed that the difference between men and women in the stability of CPM could not be ed for by any demographic e.

Our findings suggest that CPM paradigms possess sufficient reliability to be incorporated into bedside clinical evaluation of patients with chronic pain, but only among women. Volume 14Issue The full text of this article hosted at iucr.

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Marc O. Tel: ; Fax: ; E-mail: momartel. Search for more papers by this author. First published: 07 August The authors have no financial interests in the of this research and no conflicts of interest.

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Log in. Abstract Objectives To examine the temporal stability of conditioned pain modulation CPMformerly termed diffuse noxious inhibitory controls, among a sample of patients with chronic pain. De, Subjects, and Methods In this test-retest study, patients underwent a series of standardized psychophysical pain-testing procedures deed to assess CPM on two separate occasions i. Conclusions Our findings suggest that CPM paradigms possess sufficient reliability to be incorporated into bedside clinical evaluation of patients with chronic pain, but only among women.

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